The impact of molecular tumor profiling on the design strategies for targeting myeloid leukemia and EGFR/CD44-positive solid tumors

• Nikola Geskovski,
• Nadica Matevska-Geshkovska,
• Simona Dimchevska Sazdovska,
• Marija Glavas Dodov,
• Kristina Mladenovska and
• Katerina Goracinova

Beilstein J. Nanotechnol. 2021, 12, 375–401, doi:10.3762/bjnano.12.31

• feasibility of the development of FR β-targeted delivery systems [48][49]. Even though the concept of FR β targeting seems conceptually feasible, the heterogenicity of the FR β expression levels in CML and AML presents a confounding issue, which can be usually resolved by co-treatment with all-trans retinoic

• acid (ATRA) or other agonists of nuclear receptors for retinoids [50]. Such approach was demonstrated by Pan and co-workers, who formulated doxorubicin (Dox)-loaded DSPE/cholesterol/PEG liposomes decorated with folic acid and evaluated their effects upon leukemia cells both in vitro and in vivo. The

Lipid nanostructures for antioxidant delivery: a comparative preformulation study

• Elisabetta Esposito,
• Maddalena Sguizzato,
• Markus Drechsler,
• Paolo Mariani,
• Federica Carducci,
• Claudio Nastruzzi,
• Giuseppe Valacchi and
• Rita Cortesi

Beilstein J. Nanotechnol. 2019, 10, 1789–1801, doi:10.3762/bjnano.10.174

• retinoic acid, have been shown to improve skin condition and even counteract the effects of exogenous stress factors such as smoking on skin aging. This work describes the design and development of lipid nanoparticles containing antioxidant agents (α-tocopherol or retinoic acid) to protect human skin

• lipid carriers (NLCs); retinoic acid; skin pollution; solid lipid nanoparticles (SLNs); Introduction Air pollution increasingly affects industrialized urban areas in a negative manner with dramatic consequences for the environment and human health. This problem also affects rural areas, worsening the

• and skin barrier improvement [17][18][19]. Vitamin A is defined as a group of lipophilic retinoids, including retinoic acid (RA), derived from food and stored in the liver. Due to its antioxidant action, RA plays a role in cancer chemoprevention and differentiation [20]. Particularly, RA has been

Electro-optical interfacial effects on a graphene/π-conjugated organic semiconductor hybrid system

• Karolline A. S. Araujo,
• Luiz A. Cury,
• Matheus J. S. Matos,
• Thales F. D. Fernandes,
• Luiz G. Cançado and
• Bernardo R. A. Neves

Beilstein J. Nanotechnol. 2018, 9, 963–974, doi:10.3762/bjnano.9.90

• , Brazil Universidade Federal de Ouro Preto – UFOP, Ouro Preto, Brazil 10.3762/bjnano.9.90 Abstract The influence of graphene and retinoic acid (RA) – a π-conjugated organic semiconductor – interface on their hybrid system is investigated. The physical properties of the interface are assessed via scanning

• of graphene-based devices, SAM surface functionalization is employed for both doping level control and work function tuning [14][15][16]. The present work brings these two fronts together by investigating a graphene/retinoic acid (RA) – a π-conjugated organic semiconductor – hybrid system and its

• produced ultrathin 2D-like RA films. Figure 1 summarizes the morphological characterization of retinoic acid self-assembled films on graphite microplates prepared via spin-coating (see Experimental section). Since the adsorbing species interaction with monolayer graphene can be largely influenced by the